Compositions for providing a protective barrier

ABSTRACT

A composition provides a protective barrier and includes glyceryl dibehenate, tribehenin, and glyceryl behenate, a surfactant that includes glyceryl stearate, one or more fatty compounds, and one or more triglyceride. The composition optionally includes a hydrating agent and may be essentially free of or is devoid of one or more of petrolatum, mineral oil and water. The composition provides occlusivity and hydration effects that are comparable to compositions that include one or more of petrolatum, mineral oil and lanolin.

FIELD OF THE INVENTION

The invention relates to protective barrier compositions that provide aprotective occlusive barrier when applied to keratinous substrates, forexample, human skin and human hair.

BACKGROUND OF THE INVENTION

Topical formulations for keratinous substrates, for example skin, caninclude occlusive ingredients. The occlusive ingredients provide abarrier that protects against water loss and incursion of irritants andcontaminants. Well known occlusive ingredients include hydrocarbons, forexample in the form of petrolatum (petroleum jelly), and mineral oils,each of which have been included in a wide variety of skin and hairproducts. Such products are known for their spreadable texture andshapability, and their effectiveness in preventing water loss andpreserving hydration of skin and hair. Despite these beneficialfeatures, petrolatum, mineral oil and lanolin can have unpleasanttactile and aesthetic properties, including one or more of waxiness,stickiness and warming sensation. And these materials can present healthand environmental concerns.

There is a need for a composition that overcomes one or more of theaforementioned drawbacks associated with products that employ one ormore of petrolatum, mineral oil and lanolin. Such a composition wouldprovide one or more of good spreadability, pleasant tactile andaesthetic properties, and a protective barrier that preserves hydration,for example in the skin and hair, in a manner that is at leastcomparable to that of petrolatum and mineral containing products.

BRIEF SUMMARY OF THE INVENTION

The summary is provided to introduce a selection of concepts in asimplified form that are further described below in the detaileddescription of the invention. This summary is not intended to identifykey features of the claimed subject matter, nor is it intended to beused as an aid in determining the scope of the claimed subject matter.

The protective barrier composition and methods of making them arecharacterized, in various embodiments, as comprising an emollient blendcomprising glyceryl dibehenate, tribehenin and glyceryl behenate; asurfactant comprising glyceryl stearate; and a plurality of fattycompounds, the plurality of fatty compounds including one or more fattyplant derived oil or synthetic oil that comprises one or more fattychain having a chain length from and including C8 to C24, and one ormore triglycerides.

In some embodiments the emollient blend and the surfactant comprisingglyceryl stearate, in combination, is present in the composition at aconcentration up to and including about 30% by weight, based on theweight of the protective barrier composition.

In some embodiments, the plurality of fatty compounds is present in thecomposition at a concentration, by weight, of at least about 70%, basedon the total weight of the protective barrier composition. In someparticular embodiments, the plurality of fatty compounds is present inthe composition at a concentration, by weight, of between about 70% toabout 80%, based on the total weight of the protective barriercomposition.

In some embodiments, each of the emollient blend and the surfactantcomprising glyceryl stearate is present in the composition at aconcentration, by weight, at least 2%, based on the total weight of theprotective barrier composition. In some embodiments, each of theemollient blend and the surfactant comprising glyceryl stearate ispresent in the composition at a concentration, by weight, from about 2%to about 20%, based on the total weight of the protective barriercomposition. In some embodiments, the emollient blend and the surfactantcomprising glyceryl stearate are present at a ratio of 1:1, by weight,based on the weight of the protective barrier composition.

The one or more triglyceride may comprise one or more triglycerides, theone or combination present in the composition at a concentration, byweight, of between about 20% to about 50%, based on the total weight ofthe protective barrier composition. In some embodiments, the one or moretriglycerides that is present in the plurality of fatty compounds isselected from caprylic/capric triglyceride, triglycerides having a chainlength from and including C10 to C18, and combinations thereof.

In accordance with the various embodiments, the protective barriercomposition comprises one or more compounds selected from hydratingagents and solvents, and may further comprise any one or more, each, ofactives, chelating agents, silicone oils, clays, conditioning agents,and combinations thereof, together with other suitable additives.

In some embodiments, the protective barrier composition is essentiallyfree or devoid of one or more of petrolatum, mineral oil, lanolin andwater. In some particular embodiments, the protective barriercomposition is devoid of one or more of petrolatum, mineral oil, lanolinand water. In some particular embodiments, the protective barriercomposition is devoid of petrolatum, mineral oil, lanolin and water. Insome embodiments, the protective barrier composition is essentiallydevoid of water other than trace amounts (i.e., present at aconcentration that does not exceed 5% by weight, and more preferably notmore than 1% by weight, based on the weight of the composition). And insome embodiments, the protective barrier composition is essentially freeor devoid of preservatives.

In accordance with the various embodiments, the composition provides aprotective occlusive barrier to keratinous tissue. In some examples, thecomposition that lacks one or more of petrolatum, mineral oil andlanolin exhibits physical properties including viscosity, spreadability,rheology that is comparable to products containing one or more ofpetrolatum, mineral oil and lanolin.

Other features and advantages of the present invention will be apparentfrom the following more detailed description, by way of example, theprinciples of the invention.

This disclosure describes particular embodiments in accordance with thegeneral inventive concepts and is not intended to limit the scope of theinvention in any way. Indeed, the invention as described in thespecification is broader than and unlimited by the particularembodiments set forth herein, and the terms used herein have their fullordinary meaning.

DETAILED DESCRIPTION OF THE INVENTION

The term “occlusive barrier” as used herein means and refers to acomposition that includes agents that form an occlusive barrier thatminimizes or prevents water loss from skin.

The term “anhydrous” as used herein means that a composition isanhydrous in that water has not been added as a component. In someembodiments, a composition is devoid of water. Those of skill in the artwill appreciate that water may be present in a composition via one ormore of its presence in the formulation components, processingconditions and absorption from the atmosphere; thus, in some embodimentsa composition may be “essentially anhydrous” wherein water is present ata concentration that does not exceed 5% by weight, and more preferablynot more than 1% by weight, based on the weight of the composition.

The terms “petrolatum—free” and “mineral oil—free” as used herein meanthat a composition lacks one or more of petrolatum, mineral oil andlanolin. Those of skill in the art will appreciate that one or more ofpetrolatum, mineral oil and lanolin may be present in a composition viaone or more of its presence in the formulation components and processingcondition. Accordingly, in some embodiments, a composition may be“essentially free” from one or more of petrolatum, mineral oil andlanolin, wherein one or more of petrolatum, mineral oil and lanolin ispresent at a concentration that does not exceed 5% by weight, and morepreferably not more than 1% by weight, based on the weight of thecomposition. In some embodiments, one or more of petrolatum, mineral oiland lanolin has not been added as a component in the composition. Insome embodiments, a composition is devoid of one or more of petrolatum,mineral oil and lanolin.

The term “plant derived oils” as used herein means fatty plant derivedoils that contain one or more fatty chain, and in some embodiments thefatty chain has a chain length from and including C8 to C24. Thus, insome embodiments, a fatty derived plant oil may comprise one or a blendof oils having a chain length of C8, C9, C10, C11, C12, C13, C14, C15,C16, C17, C18, C19, C20, C21, C22, C23, and C24.

The term “triglycerides” as used herein means one or more ofcaprylic/capric triglyceride, and triglycerides having a chain lengthfrom and including C10 to C18. Thus, in some embodiments, triglyceridesmay comprise one or a blend of triglycerides having a chain length ofC10, C11, C12, C13, C14, C15, C16, C17, and C18.

According to the disclosure, an composition is provided for providing aprotective barrier, the composition comprising an emollient blend thatincludes glyceryl dibehenate, tribehenin and glyceryl behenate, asurfactant that includes glyceryl stearate, and one or more fattycompounds that include one or more fatty plant derived oil or syntheticoil that comprises one or more fatty chain having a chain length fromand including C8 to C24. In some embodiments, the composition comprisesone or more triglyceride. In some embodiments, the compositions compriseone or more of hydrating agents, solvents, actives, vitamins, chelatingagents. In some embodiments, the protective barrier composition isessentially free of or is devoid of one or more of petrolatum, mineraloil and lanolin. In some embodiments, the protective barrier compositionis essentially free of or is devoid of water.

The composition provides occlusivity when applied to skin to helpmaintain a favorable environment maintenance of skin hydration, and forskin healing. In some particular embodiments, the composition is free ofpetrolatum, mineral oil and lanolin. The composition provides thesurprising and unexpected benefits of a unique texture that mimics thethickness and spreadability of hydrocarbon and mineral oil-basedocclusive barrier products. Also, surprisingly, the occlusivity andhydration effects of the composition are comparable to compositions thatinclude one or more of petrolatum, mineral oil and lanolin.

Emollient Blend

In accordance with the disclosure, provided are compositions thatcomprise an emollient blend comprising glyceryl dibehenate, tribeheninand glyceryl behenate. In accordance with the various embodiments, theemollient blend comprises the raw materials comprising glyceryldibehenate, tribehenin and glyceryl behenate, each, alone or as blended,may be provided in a solvent.

In accordance with the various embodiments, each of the emollient blendcomponents glyceryl dibehenate, tribehenin and glyceryl behenate may bepresent in a composition in a ratio of from about 1:1 to about 3:1, byweight, based on the weight of the emollient blend. In otherembodiments, the emollient blend comprises glyceryl dibehenate,tribehenin and glyceryl behenate present, at a ratio of about 3:2:1, byweight, based on the weight of the emollient blend.

As used herein, glyceryl dibehenate is used to refer to the compoundthat is alternately identified in the art as 2-Hydroxypropane-1,3-diyldidocosanoate; Docosanoic acid, 1,1′-(2-hydroxy-1,3-propanediyl) ester;1,3-dibehenin; 1-Behenoyl-3-behenoyl-sn-glycerol; 1,2,3-Propanetriol1,3-dibehenate; 1-Docosanoyl-3-docosanoyl-sn-glycerol; andDiacylglycerol(22:0/0:0/22:0). As used herein, Tribehenin is used torefer to the compound that is alternately identified in the art as2,3-propanetriyl ester behenic acid; 1,2,3-propanetriyl ester docosanoicacid; 1,2,3-propenetriol tridocosanoate; behenic acid,1,2,3-propanetriyl ester; docosanoic acid, 1,2,3-propanetriyl ester;docosanoic acid, 1,2,3propanetriyl ester; glyceryl tribehenate;propane-1,2,3-triyl tridocosanoate; compritol 888; and docosanoin,tri-(7ci,8ci). And, as used herein, glyceryl behenate is used to referto the compound that is alternately identified in the art as2,3-dihydroxypropyl docosanoate; 2,3-dihydroxypropyl ester docosanoicacid; behenic acid monoglyceride; docodanoin, mono-; docosanoic acid,2,3-dihydroxypropyl ester; docosanoic acid, monoester with1,2,3-propanetriol; glycerin monobehenate; glycerol monobenhenate;glyceryl monobe henate; mono-docodanoin; and monoester with1,2,3-propanetriol docosanoic acid.

Surfactant

In accordance with the various embodiments, the emollient blend ispresent in the composition together with one or more surfactantcomprising glyceryl stearate, the combination being present in thecomposition at a concentration up to and including about 30% by weight,based on the weight of the protective barrier composition. In someembodiments, the combination is present in the range from about 1% toabout 30%, or from about 1% to about 25%, or from about 1% to about 10%,or from about 1% to about 7%, or from about 2% to about 6%, or fromabout 3% to about 5%, or from about 5% to about 15%, or from about 6% toabout 10%, or any suitable combination, sub-combination, range, orsub-range thereof by weight, based on the weight of the composition.

In accordance with the various embodiments, the surfactant may bepresent in the composition in a ratio of the surfactant to emollientblend of from about 2:1 to about 1:2, by weight, based on the weight ofthe protective barrier composition. Thus, in some embodiments, the oneor more surfactant comprising glyceryl stearate and the emollient blendmay be present at a ratio of 1:1, by weight, based on the weight of theprotective barrier composition.

In accordance with the various embodiments, the emollient blend ispresent in the composition at a concentration, by weight, of at leastabout 2%, based on the total weight of the protective barriercomposition.

In accordance with the various embodiments, the emollient blend ispresent in the composition at a concentration, by weight, based on thetotal weight of the protective barrier composition, in the range fromabout 0.01% to about 20%, or from about 2% to about 20%, or from about0.05% to about 10%, or from about 0.1% to about 4%, or from about 0.1%to about 3.5%, or from about 0.7% to about 1.5%, or from about 3.5% toabout 5%, or any suitable combination, sub-combination, range, orsub-range thereof by weight, based on the weight of the composition.

Thus, the emollient blend is present, by weight, based on the totalweight of the composition, each one or the combination present fromabout 0.01, 0.02, 0.03, 0.04, 0.05, 0.06, 0.07, 0.08, 0.09, 0.1, 0.2,0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11,12, 13, 14, 15, 16, 17, 18, 19 to about 20 weight percent, includingincrements and ranges therein and there between.

More particularly, each one of glyceryl dibehenate, tribehenin andglyceryl behenate is present in the composition at a concentration, byweight, based on the total eight of the protective barrier composition,in the range from about 0.01% to about 20%, or from about 2% to about20%, or from about 0.05% to about 10%, or from about 0.1% to about 4%,or from about 0.1% to about 3.5%, or from about 0.7% to about 1.5%, orfrom about 3.5% to about 5%, or any suitable combination,sub-combination, range, or sub-range thereof, by weight, based on theweight of the composition.

Thus, each one of glyceryl dibehenate, tribehenin and glyceryl behenateis present, by weight, based on the total weight, from about 0.01, 0.02,0.03, 0.04, 0.05, 0.06, 0.07, 0.08, 0.09, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6,0.7, 0.8, 0.9, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16,17, 18, 19 to about 20 weight percent, including increments and rangestherein and there between.

Fatty Compounds

In accordance with the disclosure, a plurality of fatty compounds ispresent in the composition, the plurality of fatty compounds includingone or more fatty plant derived oil or synthetic oil that comprises oneor more fatty chain having a chain length from and including C8 to C24.In accordance with some embodiments, the fatty compounds are selectedfrom one or more of castor oil, hydrogenated castor oil, hydrogenatedvegetable oil, synthetic oil. In accordance with some embodiments, thefatty compounds are selected from one or more of Ricinus communis(castor) seed oil, Prunus amygdalus dulcis (sweet almond) oil, Prunusarmeniaca (apricot) kernel oil, and Helianthus annuus (sunflower) seedoil.

In an particular embodiment, the plurality of fatty compounds includescastor oil, hydrogenated castor oil, hydrogenated vegetable oil,hydrogenated polyisobutene, Prunus amygdalus dulcis (sweet almond) oil,and Helianthus annuus (sunflower) seed oil.

In accordance with some embodiments, the plurality of fatty compoundsincludes more than two fatty compounds.

In accordance with the various embodiments, the plurality of fattycompounds is present in the composition at a concentration, by weight,of from about 1% to about 95%, or from about 50% to about 95%, or fromabout 70% to about 90%, or from about 70% to about 80%, or any suitablecombination, sub-combination, range, or sub-range thereof by weight,based on the weight of the composition.

In accordance with some embodiments, the plurality of fatty compounds ispresent in the composition at a concentration, by weight, of at leastabout 70%, based on the total weight of the protective barriercomposition. In some embodiments, the plurality of fatty compounds ispresent in the range from about 70% to about 95%, or from about 70% toabout 90%, or from about 70% to about 80%, or from about 72% to about75%, or any suitable combination, sub-combination, range, or sub-rangethereof by weight, based on the weight of the composition.

Thus, in some embodiments, the plurality of fatty compounds is present,by weight, based on the total weight of the composition, from about atleast 70, to about 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83,84, 85, 86, 87 88, 89, 90, 91, 92, 93, 94 or 95 weight percent,including increments and ranges therein and there between.

In accordance with the various embodiments, each one of the plurality offatty compounds is present in the composition at a concentration, byweight, based on the total weight of the protective barrier composition,in the range from about 0.1% to about 50%, or from about 0.5% to about50%, or from about 1% to about 20%, or from about 2% to about 20%, orfrom about 1.5% to about 15%, or from about 1.5% to about 10%, or fromabout 1.5% to about 5%, or from about 1.5% to about 2.5%, or from about2.5% to about 5%, or from about 4% to about 10%, or any suitablecombination, sub-combination, range, or sub-range thereof by weight,based on the weight of the composition.

Thus, each one of the plurality of fatty compounds is present, byweight, based on the total weight of the composition, each one or thecombination present from about 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8,0.9, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19,20, 21, 22, 23 24, 25, 26, 27, 28, 29, 30, 31, 32, 22, 34 35 36, 37, 38,39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49 to about 50 weight percent,including increments and ranges therein and there between.

Triglycerides

In accordance with the disclosure, some embodiments, the plurality offatty compounds includes one or more triglyceride. Triglycerides caninclude caprylic/capric triglyceride, triglycerides having a chainlength from and including C10 to C18, and combinations thereof. Examplesof C10 to C18 triglycerides include, for example, C10 triglyceride, C11triglyceride, etc.

In a particular embodiment, the one or more triglyceride includescaprylic/capric triglyceride together with one or more triglycerideshaving a chain length from and including C10 to C18.

In accordance with the various embodiments wherein the plurality offatty compounds includes one or more triglyceride, the one or moretriglycerides is present in the composition at a concentration, byweight, of between about 2% to about 50%, based on the total weight ofthe protective barrier composition. In accordance with the variousembodiments, the one or more triglycerides is present in the compositionat a concentration, by weight, of from about 2% to about 50%, or fromabout 2% to about 40%, or from about 10% to about 40%, or from about 20%to about 35%, or from about 22% to about 35%, or from about 25% to about35%, or from about 25% to about 45%, or from about 30% to about 45%, orany suitable combination, sub-combination, range, or sub-range thereofby weight, based on the weight of the composition.

In some embodiments, the composition comprises a plurality oftriglycerides, the combination of which is present at a concentration,by weight, of between about 20% to about 50%, based on the total weightof the protective barrier composition. In accordance with suchembodiments, each one of the plurality of triglycerides is present inthe composition at a concentration, by weight, based on the total weightof the protective barrier composition, in the range from about 1% toabout 40%, or from about 12% to about 40%, or from about 3% to about30%, or from about 3% to about 10%, or from about 5% to about 35%, orfrom about 10% to about 30%, or any suitable combination,sub-combination, range, or sub-range thereof by weight, based on theweight of the composition.

Thus, each one of or the combination of triglycerides present in theplurality of fatty compounds is present, by weight, based on the totalweight of the composition, each one or the combination present fromabout 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19,20, 21, 22, 23 24, 25, 26, 27, 28, 29, 30, 31, 32, 22, 34 35 36, 37, 38,39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49 to about 50 weight percent,including increments and ranges therein and there between.

Surfactant

In accordance with the disclosure, the composition includes one or moresurfactant comprising glyceryl stearate. In some embodiments, the one ormore surfactant may further comprise potassium stearate and/or sodiumstearate. The composition may include other stearate based surfactantcompounds.

As used herein, glyceryl stearate is used to refer to the compound thatis alternately identified in the art as octadecanoic acid, ester with1,2,3 propanetriol; self-emulsifying glyceryl monostearate; andstearine.

In accordance with the various embodiments, the one or more surfactantcomprising glyceryl stearate is present in the composition at aconcentration ranging from about 0.01% to about 20%, by weight relativeto the weight of the composition, or from about 2% to about 20%, or fromabout 0.1% to about 15%, or from about 0.1% to about 5% by weight, orfrom about 0.15% to about 4% by weight, or from about 0.5% to about3.5%, or from about 0.75 to about 1.25%, or any suitable combination,sub-combination, range, or sub-range thereof by weight, based on theweight of the composition. In some embodiments, the one or moresurfactant comprising glyceryl stearate is present from at least 0.01%,or from at least 2%. In some embodiments, one or more additionalsurfactants can be present in the composition according to thedisclosure.

Thus, the one or more surfactant comprising glyceryl stearate ispresent, alone or in combination with another surfactant, by weight,based on the total weight of the composition, each one or thecombination present from about 0.01, 0.02, 0.03, 0.04, 0.05, 0.06, 0.07,0.08, 0.09, 0.10, 0.20, 0.30, 0.40, 0.50, 0.60, 0.70, 0.80, 0.90, 1.0,2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19 to about20 weight percent, including increments and ranges therein and therebetween.

Hydrating Agent

In accordance with the disclosure, in some embodiments, one or morehydrating agents may be present in the composition. Hydrating agents maybe selected from and include any one or more synthetic and naturalhydrating agents. Nonlimiting examples of hydrating agents includeglycerin, squalane, sucrose, triacetin, monoethylene glycol, diethyleneglycol, triethylene glycol, propylene glycol, butylene glycol,dipropylene glycol, diethylene glycol, hexylene glycol, glycol etherssuch as monopropylene, dipropylene and tripropylene glycolalkyl(C₁-C₄)ethers, glycerol, xylitol, maltitol, sorbitol,pentaerythritol, inositol, pyrrolidone carboxylic acid, lactic acid,lithium chloride, acetamide MEA, sodium lactate, urea, dicyanamide,hyaluronic acid, aloe vera, honey, and seaweed extract.

In some particular embodiments, the composition includes one or morehydrating agent selected from glycerin, squalane.

In accordance with the various embodiments, the amount of the one ormore hydrating agents may be present in a composition in the range fromabout 1% to about 20%, or from about 1% to about 15%, or from about 1%to about 10%, or from about 2% to about 5%, or from about 5% to about20%, or from about 10% to about 20%, or from about 15% to about 20%, orany suitable combination, sub-combination, range, or sub-range thereofby weight, based on the weight of the composition. In some embodiments,the one or more hydrating agents is present from at least 5%, or from atleast 10%, or from at least 15%.

Thus, one or a combination of hydrating agents may be present, byweight, based on the total weight of the composition, each one or thecombination present from about 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12,13, 14, 15, 16, 17, 18, 19 to about 20 weight percent, includingincrements and ranges therein and there between.

Solvent

In accordance with the disclosure, one or more solvents may be presentin the composition. In accordance with some embodiments, the compositionincludes one or more solvents comprising a glycol. Glycols may beselected from and include, by way of nonlimiting examples, glycerin,caprylyl glycol, propylene glycol, propanediol, polyethylene glycol, andother glycols, and combinations of these.

In some particular embodiments, the one or more solvents comprises oneor more of propanediol, caprylyl glycol, and polypropylene glycol.

In accordance with the various embodiments, the amount of the one ormore solvents that may be present in the composition ranges from about0.1% to about 20%, or of from about 0.1% to about 15%, or from about0.1% to about 10%, or from about 0.1% to about 5%, or from about 0.2% toabout 4%, or from about 0.3% to about 3%, or any suitable combination,sub-combination, range, or sub-range thereof by weight, based on theweight of the composition.

Thus, one or a combination of solvents may be present, by weight, basedon the total weight of the composition, each one or the combinationpresent from about 0.10, 0.20, 0.30, 0.40, 0.50, 0.60, 0.70, 0.80, 0.90,1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19 toabout 20 weight percent, including increments and ranges therein andthere between.

Water

In accordance with the various embodiments, the compositions areessentially anhydrous or are devoid of water.

Chelating Agents

In accordance with the disclosure, in some embodiments, one or moreother components comprising chelating agents can be present in thecomposition according to the disclosure. In some particular embodiments,chelating agents are selected from sodium phytate,ethylenediaminetetraacetic acid (EDTA), tetrasodium etidronate,tetrasodium pyrophosphate, pentasodium ethylenediamine tetramethylenephosphonate, sodium staminate and combinations of these.

In some particular embodiments, chelating agents comprise sodiumphytate.

In accordance with the various embodiments, the amount of chelatingagents present in the composition can be present in the compositionaccording to the disclosure in a range from about 0.01% to about 5% byweight, or from about 0.05% to about 2% by weight, or from about 0.10%to about 1%, or from about 0.15% to about 0.5%, and from about 0.15% toabout 0.2%, or any suitable combination, sub-combination, range, orsub-range thereof by weight, based on the weight of the composition.

Thus, one or a combination of chelating agents may be present, byweight, based on the total weight, each one or the combination presentfrom about 0.01, 0.02, 0.03, 0.04, 0.05, 0.06, 0.07, 0.08, 0.09, 0.10,0.20, 0.30, 0.40, 0.50, 0.60, 0.70, 0.80, 0.90, 1.0, 2.0, 3.0, 4.0 up toabout 5.0 weight percent, including increments and ranges therein andthere between.

Actives

In accordance with the disclosure, in some embodiments, there may be oneor more actives present in the cosmetic composition. In someembodiments, actives used according to the disclosure may be selectedfrom; anti-microbial components, including, but not limited to,capryloyl glycine and sodium salicylate; antioxidants, including, butnot limited to, phenolic compounds, such as chalcones, flavones,flavanones, flavanols, dihydroflavonols, isoflavonoids, neoflavonoids,catechins, anthocyanidins, tannins, lignans, aurones, stilbenoids,curcuminoids, alkylphenols, betacyanins, capsacinoids,hydroxybenzoketones, methoxyphenols, naphthoquinones, phenolic terpenes,resveratrol, curcumin, pinoresinol, ferulic acid, hydroxytyrosol,cinnamic acid, caffeic acid, p-coumaric acid, baicalin, pine barkextract, ellagic acid; and vitamins and vitamin derivatives, such aspanthenol, tocopherol, ascorbic acid; conditioning agents such as thesilicone oil dimethicone, allantoin and dicaprylyl carbonate; clays suchas kaolin; and combinations thereof. Although the aforementionedoptional active components are given as an example, it will beappreciated that other optional components compatible with cosmeticapplications known in the art may be used.

In some particular embodiments, actives are selected from a one or acombination of capryloyl glycine, panthenol, and tocopherol;dimethicone, allantoin, dicaprylyl carbonate, and kaolin

In accordance with the various embodiments, the amount of one or moreactives, alone or in combination, present in the composition can bepresent in the composition according to the disclosure in a range fromabout 0.01% to about 20%, by weight, or from about 0.05% to about 15%,or from about 0.1% to about 10%, or from about 0.15% to about 5%, orfrom about 0.40% to about 4%, or from about 0.50% to about 2% by weight,or from about 1% to about 2%, or any suitable combination,sub-combination, range, or sub-range thereof by weight, based on theweight of the composition.

Thus, one or a combination of actives may be present, by weight, basedon the total weight of the composition, each one or the combinationpresent from about 0.01, 0.02, 0.03, 0.04, 0.05, 0.06, 0.07, 0.08, 0.09,0.10, 0.20, 0.30, 0.40, 0.50, 0.60, 0.70, 0.80, 0.90, 1.0, 2, 3, 4, 5,6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19 to about 20 weightpercent, including increments and ranges therein and there between.

Raw Materials

Compositions as described in the representative embodiments according tothe disclosure, and compositions as exemplified herein include rawmaterials selected from commercially available materials, including, forexample: Glyceryl Dibehenate & Tribehenin & Glyceryl Behenate blend;Glyceryl Stearate; Hydrogenated Castor Oil; Glyceryl Dibehenate—all RM100% except as noted.

EXAMPLES

Inventive Compositions RAW MATERIAL INV 1 INV 2 INV 3 INV 4 GLYCERYLDIBEHENATE (and) .5 5 5 5 TRIBEHENIN (and) GLYCERYL BEHENATE GLYCERYLSTEARATE 3.5 5 5 5 HYDROGENATED CASTOR 2.5 2.5 OIL HYDROGENATED 1.75 2.5VEGETABLE OIL RICINUS COMMUNIS (CASTOR) 10 SEED OIL HYDROGENATED 5POLYISOBUTENE CAPRYLIC/CAPRIC 27.05 22.5 32.5 32.5 TRIGLYCERIDE C10-1810 10 TRIGLYCERIDES HELIANTHUS ANNUUS 15 26.45 37.45 26.45 (SUNFLOWER)SEED OIL PRUNUS AMYGDALUS DULCIS 4 10 10 (SWEET ALMOND) OIL GLYCERIN 1515 15 15 CAPRYLYL GLYCOL 0.3 PROPANEDIOL 3 3 2 3 SODIUM PHYTATE 0.150.15 0.15 CAPRYLOYL GLYCINE 0.4 0.4 0.4 0.4 ACTIVES 1.5

Comparative Compositions

Aquaphor:

Active ingredient: Petrolatum (41%); Inactive ingredients: Mineral Oil,Ceresin, Lanolin Alcohol, Panthenol, Glycerin, Bisabolol

Aqua Baume: silicone and water emulsion

Inventive and Comparative Testing:

Transepidermal Water Loss (TEWL) may be determined in a bench system(simulating live skin) which evaluates skin barrier performance oftested compositions. TEWL testing can include use of an automated systemwhich measures water loss from a chamber through a treated membrane overan extended period of time with controlled temperature and humidity.According to the method, fixed volumes of water are deposited in eachchamber and fixed amounts of each tested composition applied to themembrane of each respective test chamber. The lower the TEWL water lossflux value, the less water loss would be expected through the skin, andthus the greater occlusive barrier protection.

Test results with inventive compositions that include the emollientcomposition with the surfactant and fatty compounds have been obtainedthat show performance comparable to mineral oil-based compositions. Asexpected, the greatest water loss was observed with the Aqua Baumecontrol (˜265 g m⁻² h⁻¹) which lacks any occlusive components. Thesetest results demonstrate that inventive compositions comprising theemollient composition, surfactant and fatty compounds according to thedisclosure provide an occlusive barrier that is surprisingly comparableto that provided by a conventional mineral-oil based composition.

The articles “a” and “an,” as used herein, mean one or more when appliedto any feature in embodiments of the present invention described in thespecification and claims. The use of “a” and “an” does not limit themeaning to a single feature unless such a limit is specifically stated.The article “the” preceding singular or plural nouns or noun phrasesdenotes a particular specified feature or particular specified featuresand may have a singular or plural connotation depending upon the contextin which it is used. The adjective “any” means one, some, or allindiscriminately of whatever quantity.

“One or more,” as used herein, means at least one, and thus includesindividual components as well as mixtures/combinations.

The transitional terms “comprising”, “consisting essentially of” and“consisting of”, when used in the appended claims, in original andamended form, define the claim scope with respect to what unrecitedadditional claim elements or steps, if any, are excluded from the scopeof the claim(s). The term “comprising” is intended to be inclusive oropen-ended and does not exclude any additional, unrecited element,method, step or material. The term “consisting of” excludes any element,step or material other than those specified in the claim and, in thelatter instance, impurities ordinary associated with the specifiedmaterial(s). The term “consisting essentially of” limits the scope of aclaim to the specified elements, steps or material(s) and those that donot materially affect the basic and novel characteristic(s) of theclaimed invention. All materials and methods described herein thatembody the present invention can, in alternate embodiments, be morespecifically defined by any of the transitional terms “comprising,”“consisting essentially of,” and “consisting of.”

Other than in the operating examples, or where otherwise indicated, allnumbers expressing quantities of ingredients and/or reaction conditionsare to be understood as being modified in all instances by the term“about,” meaning within 10% of the indicated number (e.g. “about 10%”means 9%-11% and “about 2%” means 1.8%-2.2%).

All percentages and ratios are calculated by weight unless otherwiseindicated. All percentages are calculated based on the total compositionunless otherwise indicated. Generally, unless otherwise expressly statedherein, “weight” or “amount” as used herein with respect to the percentamount of an ingredient refers to the amount of the raw materialcomprising the ingredient, wherein the raw material may be describedherein to comprise less than and up to 100% activity of the ingredient.Therefore, weight percent of an active in a composition is representedas the amount of raw material containing the active that is used, andmay or may not reflect the final percentage of the active, wherein thefinal percentage of the active is dependent on the weight percent ofactive in the raw material.

All ranges and amounts given herein are intended to include subrangesand amounts using any disclosed point as an end point. Thus, a range of“1% to 10%, such as 2% to 8%, such as 3% to 5%,” is intended toencompass ranges of “1% to 8%,” “1% to 5%,” “2% to 10%,” and so on. Allnumbers, amounts, ranges, etc., are intended to be modified by the term“about,” whether or not so expressly stated. Similarly, a range given of“about 1% to 10%” is intended to have the term “about” modifying boththe 1% and the 10% endpoints. Further, it is understood that when anamount of a component is given, it is intended to signify the amount ofthe active material unless otherwise specifically stated.

Notwithstanding that the numerical ranges and parameters setting forththe broad scope of the disclosure are approximations, unless otherwiseindicated the numerical values set forth in the specific examples arereported as precisely as possible. Any numerical value, however,inherently contains certain errors necessarily resulting from thestandard deviation found in their respective testing measurements. Theexample that follows serves to illustrate embodiments of the presentdisclosure without, however, being limiting in nature.

While the invention has been described with reference to a preferredembodiment, it will be understood by those skilled in the art thatvarious changes may be made and equivalents may be substituted forelements thereof without departing from the scope of the invention. Inaddition, many modifications may be made to adapt a particular situationor material to the teachings of the invention without departing from theessential scope thereof. Therefore, it is intended that the inventionnot be limited to the particular embodiment disclosed as the best modecontemplated for carrying out this invention, but that the inventionwill include all embodiments falling within the scope of the appendedclaims.

1. A protective barrier composition, comprising: (i) an emollient blendcomprising glyceryl dibehenate, tribehenin and glyceryl behenate; (ii) asurfactant comprising glyceryl stearate; (iii) a plurality of fattycompounds, the plurality of fatty compounds including one or more fattyplant derived oil or synthetic oil that comprises one or more fattychain having a chain length from and including C8 to C24; and (iv) oneor more triglycerides present in the composition at a concentration, byweight, in the range from about 20% to about 50%, based on the totalweight of the protective barrier composition.
 2. A protective barriercomposition of claim 1, wherein the emollient blend and the surfactantcomprising glyceryl stearate, in combination, is present in thecomposition at a concentration up to and including about 30% by weight,based on the weight of the protective barrier composition.
 3. Aprotective barrier composition of claim 1, wherein the emollient blendcomprises glyceryl dibehenate, tribehenin and glyceryl behenate present,by weight, at a ratio of 1:1:1, based on the weight of the emollientblend.
 4. A protective barrier composition of claim 1, wherein theemollient blend comprises glyceryl dibehenate, tribehenin and glycerylbehenate present, by weight, at a ratio of about 3:2:1, based on theweight of the emollient blend.
 5. A protective barrier composition ofclaim 1, wherein each of the emollient blend and the surfactantcomprising glyceryl stearate is present in the composition at aconcentration, by weight, of at least about 2% and up to about 20%,based on the total weight of the protective barrier composition.
 6. Aprotective barrier composition of claim 1, wherein the emollient blendis present in the composition at a concentration, by weight, in therange from about 2% to about 20%, based on the total weight of theprotective barrier composition.
 7. A protective barrier composition ofclaim 1, wherein the surfactant comprising glyceryl stearate is presentin the composition at a concentration, by weight, in the range fromabout 2% to about 20%, based on the total weight of the protectivebarrier composition.
 8. A protective barrier composition of claim 1,wherein the emollient blend and the surfactant comprising glycerylstearate are present at a ratio of 1:1, by weight, based on the weightof the protective barrier composition.
 9. A protective barriercomposition of claim 1, wherein the plurality of fatty compounds arepresent in the composition at a concentration, by weight, of at leastabout 70%, based on the total weight of the protective barriercomposition.
 10. A protective barrier composition of claim 1, whereinthe plurality of fatty compounds are present in the composition at aconcentration, by weight, in the range from about 70% to about 80%,based on the total weight of the protective barrier composition.
 11. Aprotective barrier composition of claim 1, the composition comprising inthe plurality of fatty compounds one or more of castor oil, hydrogenatedcastor oil, hydrogenated vegetable oil, synthetic oil.
 12. A protectivebarrier composition of claim 1, the composition further comprising inthe plurality of fatty compounds one or more of Prunus amygdalus dulcis(sweet almond) oil, and Helianthus annuus (sunflower) seed oil.
 13. Aprotective barrier composition of claim 1, wherein the one or moretriglyceride is present in the composition at a concentration, byweight, in the range from about 25% to about 45%, based on the totalweight of the protective barrier composition.
 14. A protective barriercomposition of claim 13, wherein the one or more triglycerides isselected from caprylic/capric triglyceride, triglycerides having a chainlength from and including C10 to C18, and combinations thereof.
 15. Aprotective barrier composition of claim 1, the composition comprisingone or more hydrating agent present in the composition at aconcentration, by weight, in the range from about 10% to about 20%,based on the total weight of the protective barrier composition.
 16. Aprotective barrier composition of claim 15, the composition comprisingone or more hydrating agents selected from glycerin and squalane, andcombinations thereof.
 17. A protective barrier composition of claim 1,the composition comprising one or more solvent present in thecomposition at a concentration, by weight, in the range from about 1% toabout 20%, based on the total weight of the protective barriercomposition.
 18. A protective barrier composition of claim 17, thecomposition comprising one or more solvent selected from glycols.
 19. Aprotective barrier composition of claim 18, the composition comprisingone or more solvent selected from propanediol, caprylyl glycol,polypropylene glycol, and combinations thereof.
 20. A protective barriercomposition of claim 1, the composition comprising one or more compoundsselected from actives, vitamins, chelating agents, silicone oils, clays,conditioning agents, and combinations thereof.
 21. A protective barriercomposition of claim 20, comprising one or more of capryloyl glycine,tocopherol, panthenol, sodium phytate, dimethicone, allantoin,dicaprylyl carbonate, and kaolin.
 22. A protective barrier compositionof claim 1, wherein the protective barrier composition is essentiallyfree of one or more of petrolatum, mineral oil and lanolin.
 23. Aprotective barrier composition of claim 1, wherein the composition isessentially anhydrous.
 24. A protective barrier composition, comprising:(i) an emollient blend comprising glyceryl dibehenate, tribehenin andglyceryl behenate; (ii) a surfactant comprising glyceryl stearate;wherein each of the emollient blend and the surfactant is present in thecomposition at a concentration, by weight, in the range from about 2% toabout 20%, based on the total weight of the protective barriercomposition, and wherein the combination of the emollient blend and thesurfactant is present in the composition at a concentration, by weight,of up to and including about 30%, based on the total weight of theprotective barrier composition; (iii) a plurality of fatty compoundsincluding one or more fatty plant derived oil or synthetic oil thatcomprises one or more fatty chain having a chain length from andincluding C8 to C24, present in the composition at a concentration, byweight, of at least about 70%, based on the total weight of theprotective barrier composition; and (iv) one or more triglyceridespresent in the composition at a concentration, by weight, in the rangefrom about 20% to about 50%, based on the total weight of the protectivebarrier composition.
 25. A protective barrier composition of claim 24,the composition comprising one or more compounds selected from wax,actives, vitamins, chelating agents, silicone oils, clays, conditioningagents, and combinations thereof.
 26. A protective barrier compositionof claim 25, comprising one or more of glycerin, capryloyl glycine,panthenol, tocopherol, sodium phytate, dimethicone, allantoin,dicaprylyl carbonate, and kaolin.
 27. A protective barrier compositionof claim 24, wherein the protective barrier composition excludespetrolatum, mineral oil and lanolin and is essentially anhydrous.
 28. Aprotective barrier composition, comprising: (i) an emollient blendcomprising glyceryl dibehenate, tribehenin and glyceryl behenate; (ii) asurfactant comprising glyceryl stearate; (iii) a plurality of fattycompounds, the plurality of fatty compounds comprising: one or more ofcastor oil, hydrogenated castor oil, hydrogenated vegetable oil, andhydrogenated polyisobutene; one or more triglycerides selected fromcaprylic/capric triglyceride and triglycerides having a chain lengthfrom and including C10 to C18, the one or more triglycerides present inthe composition at a concentration, by weight, in the range from about20% to about 50%, based on the total weight of the protective barriercomposition; and one or more fatty compounds selected from Prunusamygdalus dulcis (sweet almond) oil, Helianthus annuus (sunflower) seedoil, Helianthus annuus (sunflower) seed oil; and (iv) one or morehydrating agent; wherein the protective barrier composition excludes oneor more of petrolatum, mineral oil and lanolin and water.
 29. Aprotective barrier composition according to claim 28, wherein theemollient blend in combination with the surfactant is present in thecomposition at a concentration, by weight, of up to and including about30%, based on the total weight of the protective barrier composition,and wherein the plurality of fatty compounds is present in thecomposition at a concentration, by weight, of at least about 70%, basedon the total weight of the protective barrier composition and compriseshydrogenated vegetable oil, hydrogenated polyisobutene, caprylic/caprictriglyceride, one or a mixture of triglycerides, each having a chainselected length from C10 to C18, Prunus amygdalus dulcis (sweet almond)oil, and Helianthus annuus (sunflower) seed oil.
 30. A protectivebarrier composition according to claim 29, further comprising one ormore wax, actives, vitamins, chelating agents, silicone oils, clays,conditioning agents, and combinations thereof.
 31. A protective barriercomposition according to claim 30, further comprising one or more ofglycerin, capryloyl glycine, panthenol, tocopherol, sodium phytate,dimethicone, allantoin, dicaprylyl carbonate, and kaolin.
 32. Aprotective barrier composition of claim 31, wherein the protectivebarrier composition excludes petrolatum, mineral oil and lanolin and isessentially anhydrous.